Moderate- to high-intensity treatment is used, and there are no target lipid levels (see table Statins for ASCVD Prevention in Dyslipidemia). Our new CrystalGraphics Chart and Diagram Slides for PowerPoint is a collection of over 1000 impressively designed data-driven chart and editable diagram s guaranteed to impress any audience. Continuous subcutaneous insulin infusion pumps can eliminate the need for multiple daily injections, provide maximal flexibility in the timing of meals, and substantially reduce variability in glucose levels. Day .6 Exam Prometric. Powers MA, Bardsley J, Cypress M, et al: Diabetes Self-management Education and Support in Type 2 Diabetes: A Joint Position Statement of the American Diabetes Association, the American Association of Diabetes Educators, and the Academy of Nutrition and Dietetics. Oral antihyperglycemic drugs may, Enhance pancreatic insulin secretion (secretagogues), Sensitize peripheral tissues to insulin (sensitizers), Impair gastrointestinal absorption of glucose. - Diabetes Mellitus Dr. Ricardo Curc Historia Descrita en el manuscrito de Ebers en el 1500 BC, se presume, de casos de DM1. It is at least as effective as sulfonylureas in reducing plasma glucose, rarely causes hypoglycemia, and can be safely used with other drugs and insulin. Below are review notes for Diabetes Mellitus to help you study for the NCLEX exam or your nursing lecture exams. Endocrine Society: Clinical Practice Guidelines: provides guideleines on evaluation and management of patients with diabetes as well as links to other information for clinicians. Diabetes Care 41(12): 2669–2701, 2018. At mealtime, user, Multiple daily injects (MDI) and frequent SMBG, Due to too much insulin in relation to glucose, Hypertrophy or atrophy of SQ tissue r/t frequent, Work to improve the mechanisms in which insulin, Enhance insulin sensitivity and glucose transport, Slow absorption of carbohydrate in intestine, Increase the insulin secretion glucose dependent, Incretins (DPP4 inhibitors, GLP1 analogs), Diet based on usual food intake, balanced with, Emphasis placed on achieving glucose, lipid, and, Take small carbohydrate snacks Q 30 min during, Monitor blood glucose levels before, during, and. SGLT2 inhibitors may also cause modest weight loss and lowering of blood pressure. What are the possible causes of Diabetes Mellitus? A correction factor, also known as the insulin sensitivity factor, is the amount that 1 unit of insulin will lower a patient's blood glucose level over 2 to 4 hours; this factor is often calculated using the "1800 rule" when rapid-acting insulin is used for correction (1800/total daily dose of insulin). Diabetes Care 38(7):1372–1382, 2015. If left untreated, diabetes can cause many complications. Other premixed formulations include NPA (neutral protamine aspart or a form of aspart modified to act like NPH) with insulin aspart and a formulation of premixed degludec and aspart. The report provides key statistics on the market status of the Type 2 Diabetes Mellitus Therapeutics manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry. ACE inhibitors or ARBs are indicated for patients with evidence of early diabetic nephropathy (albuminuria), even in the absence of hypertension, and are a good choice for treating hypertension in patients who have diabetes mellitus and who have not yet shown renal impairment. The link you have selected will take you to a third-party website. - The prevalence of diabetes mellitus (DM) is proliferating in the Netherlands. INTRODUCTION — Initial treatment of patients with type 2 diabetes mellitus includes lifestyle changes focusing on diet, increased physical activity and exercise, and weight reduction, reinforced by consultation with a registered dietitian and diabetes self-management education, when possible. Patients with type 2 diabetes mellitus are often initially treated with diet and exercise. Liraglutide also comes as a combination pen with insulin degludec. Pioglitazone may increase the risk of bladder cancer (although data are conflicting), heart failure, and fractures. Garber AJ, Handelsman Y, Grunberger G, et al: Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm--2020 executive summary. Country’s diabetes care is largely focused on primary health care, with the responsibility of general practitioners for most areas of care. Mar 29, 2018 DTN Staff. For these reasons, some physicians hospitalize hypoglycemic patients, especially older ones. Most insulin preparations are now recombinant human, practically eliminating the once-common allergic reactions to the drug when it was extracted from animal sources. Prevalence of type 2 diabetes mellitus in patients with heart failure. - Diabetes Mellitus Munir Gharaibeh, MD, PhD, MHPE Faculty of Medicine The Jordan University August 2015 * Munir Gharaibeh, MD, PhD, MHPE * Oral Hypoglycemic Agents ... - Title: Diabetes Mellitus Author: FK063 Last modified by: FK063 Created Date: 9/28/2006 7:34:08 AM Document presentation format: Bildschirmpr sentation, - Title: MAPA e Diabetes Subject: Tese Paulo Author: Sandra Roberta G Ferreira Keywords: MAPA Hipertens o Diabetes DM Description: Disc Med Preventiva, - Diabetes Mellitus Failure to control blood glucose Long term health complications Atherosclerosis Stroke Neuropathy (damaged nerves) Retinopathy, glaucoma. Carcinoma; CARDIOLOGY ppt. Circulating anti-insulin antibodies are a very rare cause of insulin resistance. Well-tolerated but cause only modest improvements in hemoglobin A1C, A slight increase in risk of pancreatitis seen in several studies, Glucagon-like peptide-1 (GLP1) receptor agonists, Mimic the effects of GLP-1, a peptide made in the small intestine that enhances glucose-dependent insulin secretion, 3 mg once a day, increasing after 30 days to 7 mg once a day. Insulin degludec (another long-acting insulin) has an even longer duration of action of over 40 hours. Many prefilled insulin pen devices are available as an alternative to the conventional vial and syringe method. The amylin analog pramlintide mimics amylin, a pancreatic beta-cell hormone that helps regulate postprandial glucose levels. EMBRYOLOGY PPT. Annan autoimmun sjd? Do you have PowerPoint slides to share? The available systems still require user input for bolus doses. Regular monitoring of blood glucose levels is essential to prevent complications of diabetes. Chlorpropamide also causes the syndrome of inappropriate ADH secretion. Associated with? In general, the simplest effective regimen is preferred. For More Info, click on : Lixisenatide is also available in a combination pen with insulin glargine. Which of the following types of thyroid cancer accounts for 80 to 90% of all cases? A common complication is weight gain, which is mostly attributable to reduction in loss of glucose in urine and improved metabolic efficiency. The legacy of this great resource continues as the MSD Manual outside of North America. When a person with diabetes neglects this important aspect of diabetes management, then his/her blood sugars become uncontrolled. Patients with type 1 diabetes mellitus of long duration may be unaware of hypoglycemic episodes because they no longer experience autonomic symptoms (hypoglycemia unawareness). FDA concerns regarding diabetes mellitus drug development were furthered in part by a meta-analysis of several small trials suggesting excess risk with the drug rosiglitazone. Many of them are also animated. Emergency ppt. Typically, 15 g of glucose or sucrose should be ingested. Patients should check their glucose levels 15 minutes after glucose or sucrose ingestion and ingest an additional 15 g if their glucose level is not > 80 mg/dL (> 4.4 mmol/L). Neutral protamine Hagedorn (NPH, or insulin isophane) is intermediate-acting; onset of action is about 2 hours after injection, peak effect is 4 to 12 hours after injection, and duration of action is 18 to 26 hours. To maintain this constant source of energy, blood glucose levels must be kept ... Best Diabetes Consultant Clinic | Diet Tips for Diabetes in Gurgaon, - Dietcare by Diksha provides Best Diet Plans for Diabetes, Food to Eat, Food to Avoid, Diet Plans for Diabetes, Diabetes Reversal in South Delhi, Gurgaon, Faridabad. In most cases, in women who become pregnant, insulin should replace non- insulin antihyperglycemic drugs. Whether your application is business, how-to, education, medicine, school, church, sales, marketing, online training or just for fun, is a great resource. the following generally favour the diagnosis of insulin-dependent diabetes mellitus: — acute onset — onset at young age (20 years and younger) * In the absence of obvious symptoms, only if value is confirmed at least once. That's all free as well! These recommendations are for initiation of therapy; thereafter, choice of regimens generally rests on physiologic response and patient and physician preferences. They are all artistically enhanced with visually stunning color, shadow and lighting effects. Weight gain, due to fluid retention and increased adipose tissue mass, is common and may be substantial (> 10 kg) in some patients. In older patients, hypoglycemia may cause strokelike symptoms of aphasia or hemiparesis and is more likely to precipitate stroke, myocardial infarction, and sudden death. J Clin Endocrinol Metab  101(11):3922-3937, 2016. However, worsening of insulin secretion and insulin resistance is probably more a feature of diabetes mellitus itself than of drugs used to treat it. Hypoglycemia is the most common complication of insulin treatment, occurring more often as patients try to achieve strict glucose control and approach near-normoglycemia. How To Control Brittle Diabetes Mellitus? DIABETES MELLITUS ppt. A more common cause of unexplained morning hyperglycemia, however, is a rise in early morning growth hormone (dawn phenomenon). Cochrane Database Syst Rev 2019; 12:CD008558. For patients < 40 or > 75, statins are given based upon individual assessment of the risk:benefit ratio and patient preference. - This power point presentation describes about How To Control Brittle Diabetes Mellitus? For patients who are unconscious or unable to swallow, hypoglycemia can be treated immediately with glucagon 1 mg given subcutaneously or intramuscularly, or with dry glucagon 3 mg intranasally, or a 50% dextrose solution 50 mL IV (25 g) followed, if necessary, by IV infusion of a 5% or 10% dextrose solution to maintain adequate plasma glucose levels. Diet is the cornerstone of therapy for diabetes mellitus. LOC, seizures, coma, death, Ingest simple CHO (fruit juice, soft drink), or, Avoid sweets with fat (slows sugar absorption), Then eat usual meal snack or meal and recheck, Treatment for hypoglycemia if not alert enough to, Glucagon 1mg IM or SQ (glycogen ? - Doss india is provide Diabetes Mellitus services in pune. Insulin is required for all patients with type 1 diabetes mellitus because they become ketoacidotic without it; it is also helpful for management of many patients with type 2 diabetes. Rapid-acting insulins, including lispro and aspart, are rapidly absorbed because reversal of an amino acid pair prevents the insulin molecule from associating into dimers and polymers. Disadvantages include cost, mechanical failures leading to interruptions in insulin supply, and the inconvenience of wearing an external device. Symptoms of mild or moderate hypoglycemia include headache, diaphoresis, palpitations, light-headedness, blurred vision, agitation, and confusion. Diabetes mellitus is one of the chronic noncommunicable diseases that have increased markedly in this century. Drug induced diabetes is when use of a specific medication has lead to the development of diabetes. The Manual was first published as the Merck Manual in 1899 as a service to the community. Surgery For Type 2 Diabetes Mellitus Helps To Recover From Diabetes, - Type 2 Diabetes Mellitus increases the risk of other long term health problems and complications, such as cardiovascular disease, neuropathies, stroke, kidney problems, depression, blindness. In addition, 2 hybrid closed-loop insulin delivery systems are available, and there are other systems in development. - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. - Assessment and Management of Patients With Diabetes Mellitus Prepared by Dr. ImanAbdullah Thank You * Out Line Definition of diabetes mellitus Risk factors for ... - Title: DIABETES MELLITUS Author: Hp Last modified by: Hp Created Date: 1/15/2013 10:52:44 PM Document presentation format: Presentaci n en pantalla (4:3), 7 consejos de diabetes mellitus tipo 2 y ayuda para diabeticos. If those measures are not sufficient for glycemic control, patients may be prescribed oral antihyperglycemic drugs, injectable glucagon-like peptide-1 (GLP-1) receptor agonists, insulin, or a combination of these drugs. Sodium-glucose co-transporter 2 (SGLT2) inhibitors (canagliflozin, dapagliflozin, empagliflozin) inhibit SGLT2 in the proximal tubule of the kidney, which blocks glucose reabsorption, thus causing glycosuria and lowering plasma glucose. Netherlands Diabetes Market will be USD 4.48 Billion by 2025 - The prevalence of diabetes mellitus (DM) is proliferating in the Netherlands. CANDIDIASIS ppt. Antidiabetic Drugs: Mechanisms of Action and Potential Outcomes on CellularMetabolism. Circulation 132: 691–718, 2015. Boasting an impressive range of designs, they will support your presentations with inspiring background photos or videos that support your themes, set the right mood, enhance your credibility and inspire your audiences. The trusted provider of medical information since 1899, Diabetes Mellitus and Disorders of Carbohydrate Metabolism. Lancet 2009;373:1773-9. Agents include renin-angiotensin-aldosterone system blockers (angiotensin-converting enzyme [ACE] inhibitors or angiotensin II receptor blockers [ARBs]), statins, and aspirin. Diabetes Mellitus: Pharmacology and Disease Management Michael King, MD ... Drug Class HbA1c % Decrease Sulfonylureas (Glyburide, Glipizde, Glimepiride) 1.0 to 2.0 Meglitinides ... –Type 2 diabetes, using insulin and not at goal. Allows self-management decisions regarding diet, Important for detecting episodic hyperglycemia, Used for patients with type 1 DM who have, Eliminates the need for exogenous insulin, Too much insulin (or oral agents) in relation to, Brain requires constant glucose supply thus, S/S of brain glucose deprivation (CNS symptoms). TZDs are as effective as sulfonylureas and metformin in reducing hemoglobin A1C. PVD (? Meneses MJ, Silva BM, Sousa M, S R, Oliveira PF, Alves MG(1). The rise in the prevalence of obesity is another point of concern, leading to a vast increase in the number of patients with metabolic syndrome. Except for use of regular insulin, which is given IV in hospitalized patients, insulin is almost always administered subcutaneously. Either may resolve by rotation of injection sites. Biguanides also lower lipid levels and may also decrease gastrointestinal nutrient absorption, increase beta-cell sensitivity to circulating glucose, and decrease levels of plasminogen activator inhibitor 1, thereby exerting an antithrombotic effect. In this case, the evening insulin dose should be increased, changed to a longer-acting preparation, or injected later. Chest X-Ray ppt. Or use it to find and download high-quality how-to PowerPoint ppt presentations with illustrated or animated slides that will teach you how to do something new, also for free. S/S dehydration (? They are considered peripheral insulin sensitizers, but their stimulation of peripheral glucose uptake may simply be a result of reductions in glucose from their hepatic effects. Antidiabetic Drugs Ppt . Bellamy L, Casas JP, Hingorani AD, Williams D. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. A correction dose (current glucose level - target glucose level/ correction factor) is the dose of insulin that will lower the blood glucose level into the target range. Metformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus. This approach is most effective when the dose of rapid- or short-acting insulin is adjusted for preprandial blood glucose level and anticipated meal content. Diabetes Tipe-1 (destruksi sel beta) Autoimun Idiopatik. Semaglutide is associated with increased progression of diabetic retinopathy. These analogs were created by modifying the human insulin molecule that alters absorption rates and duration and time to action. Na, ? - ... Usually lean and young patients but this trend in changing Non-Insulin-Dependent Diabetes Mellitus ... in Type I and Type II diabetics as an add ... - Diabetes mellitus Birgitta Wagrell ... 0,25% LADA Latent Autoimmune Diabetes in Adults Ofta (n ra) normal vikt Hereditet f r DM ej vanligt. 1. Twenty-six per cent of the diabetic subjects (19/72) had multi-drug resistant TB. Madhumeda : India, orina dulce ... - Definition Diabetes: Clinical Features Symptoms: Polyuria Polydipsia = thirst Polyphagia= appetite Asthenia & Loss of weight Leonard Thompson (14 year old boy ... Netherlands Diabetes Market will be USD 4.48 Billion by 2025. Injectable antihyperglycemic drugs other than insulin are the glucagon-like peptide-1 (GLP-1) receptor agonists and the amylin analog, pramlintide (see table Characteristics of Injectable Non-Insulin Antihyperglycemic Drugs). If insulin treatment is needed after a generalized allergic reaction, skin testing with a panel of purified insulin preparations and desensitization should be done. -GLUT-5 is also the main transporter of FRUCTOSE 3. - Diabetes is growing like a wildfire in India, turning the country as the diabetes capital of the world. The nurses role include educating, assessing, planning, administering medication, and evaluating treatment. However, intensive therapy may result in more frequent episodes of hypoglycemia and weight gain and is more effective in patients who are able and willing to take an active role in their self-care. For patients with secondary diabetes mellitus who routinely use insulin or oral hypoglycemic drugs, an additional code from category Z79 should be assigned to identify the long-term (current) use of insulin or oral hypoglycemic drugs. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. Nevertheless, periodic monitoring of liver function is recommended. Formulations are available for dosing twice a day, once a day, and weekly. Diabetes mellitus (DM), commonly known as diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. Cancer Drugs ppt. Baptiste-Roberts K, Barone BB, Gary TL, Golden SH, Wilson LM, Bass EB, et al. Examples include exenatide (an incretin hormone), lixisenatide, liraglutide, dulaglutide, albiglutide, and semaglutide. As the nurse taking care of the diabetic patient, you must know how to properly care for them, especially newly diagnosed diabetic. ID and correct precipitating cause (e.g., Occurs in Type II diabetics (often elderly), Similar to DKA, except there is enough insulin, Extreme hyperglycemia causes intracellular. The two most common forms are type 1 and type 2 diabetes mellitus. ** For diagnostic values of diabetes and impaired glucose tolerance, refer to … If needed, after another 30 days increase to 14 mg once a day, Low risk of hypoglycemia; may promote modest weight loss, Thyroid C-cell tumors (medullary carcinoma) noted in rodents, Weekly preparations may cause fewer gastrointestinal adverse effects. There is another type of diabetes as well which is called diabetes insipidus but as i mentioned that most of the times when we speak only diabetes we are actually saying about diabetes mellitus. All DPP-4 inhibitors can be used in moderate to severe renal insufficiency. types of Diabetes, Effects of Diabetes. Complications of Fracture; Contraception ppt; DENTAL LECTURE NOTES; DENTAL ppt. Short-acting insulin secretagogues (repaglinide, nateglinide) stimulate insulin secretion in a manner similar to sulfonylureas. Orthostatic symptoms can also occur. The discovery of insulin and other drugs for lowering hyperglycemia have certainly reduced mortality from acute complications of diabetes and improved the quality of life of many diabetic patients. 11.1 mmol/L plus, Impaired Glucose Tolerance Test patient is, Hemoglobin A1C test (glycosylated Hgb) gt6.5, Reflects amount of glucose attached to Hgb over, Indicates overall glucose control over previous, Prescribed for the patient with type 2 DM who. La Diabetes Mellitus (DM) es una enfermedad de alta prevalencia, reconocida como unproblemade salud p blica, debido a sus altas tasas de ... Update on Diabetes Medications and Guidelines in Cardiopulmonary Rehab Setting. - diabetes mellitus majuvy l. sulse msn, rn, ccrn lola oyedele msn, rn, ctn diabetes mellitus define chronic systemic disease characterized by either a deficiency of ... | PowerPoint PPT presentation | free to view. Such physiologic regimens allow greater freedom of lifestyle because patients can skip or time-shift meals and maintain normoglycemia. Hyperglycemia may follow hypoglycemia either because too much sugar was ingested or because hypoglycemia caused a surge in counter-regulatory hormones ( glucagon, epinephrine, cortisol, growth hormone). To view this presentation, you'll need to allow Flash. Symptoms often include frequent urination, increased thirst, and increased appetite. Symptoms of more severe hypoglycemia include seizures and loss of consciousness. When given once or twice a day, lowest starting dose may minimize nausea. Though one TZD (troglitazone) caused acute liver failure, currently available drugs have not proven hepatotoxic. When given once/day or bid, lowest starting dose may minimize nausea. There may be some weight gain, although apparently less than with sulfonylureas. Chronic Myeloid ppt. Local fat atrophy or hypertrophy at injection sites is relatively rare and is thought to result from an immune reaction to a component of the insulin preparation. According to Renub Research analysis, Netherlands Diabetes Market is forecasted to reach USD 4.48 Billion by the year 2025. Recently developed "smart" insulin pens communicate with a smart phone application to track administered insulin and make dosing recommendations. Peters AL, Ahmann AJ, Battelino T, et al: Diabetes technology—Continuous subcutaneous insulin infusion therapy and continuous glucose monitoring in adults: An Endocrine Society Clinical Practice Guideline. The drug should be withheld during surgery, administration of IV contrast, and any serious illness. DIABETES MELLITUS. Cl, ? HR ? Leading cause of heart disease, stroke, adult, Facilitates normal glucose range of 3.9 6.7, Promotes glucose transport from the bloodstream, Analogous to a key that unlocks the cell door, Stimulates storage of glucose as glycogen, Enhances fat deposition in adipose tissue, Counter-regulatory hormones (especially glucagon), When glucose unavailable during fasting state, Formerly known as juvenile onset or insulin, Most often occurs in people under 30 years of age, Progressive destruction of pancreatic ? Regimens range from twice a day split-mixed (eg, split doses of rapid- and intermediate-acting insulins) to more physiologic basal-bolus regimens using multiple daily injections (eg, single fixed [basal] dose of long-acting and variable prandial [bolus] doses of rapid-acting insulin) or an insulin pump. Spring-loaded self-injection devices (for use with a syringe) may be useful for the occasional patient who is fearful of injection, and syringe magnifiers are available for patients with low vision. - Estos Consejos te Ayudaran a Controlar la Diabetes Mellitus Tipo 2 La diabetes y el exceso de azúcar en la sangre en latinoamerica, está en marcha! It is the only insulin form for IV use. NPA = neutral protamine aspart; NPH = neutral protamine Hagedorn; NPL = neutral protamine lispro. SGLT-2 inhibitors have been implicated in causing diabetic ketoacidosis (DKA) in patients with both type 1 and type 2 diabetes and ketoacidosis may occur at lower blood glucose levels than in other causes of DKA. Learn more about our commitment to Global Medical Knowledge. Contribution of metformin to life-threatening lactic acidosis is very rare, but the drug is contraindicated in patients at risk of acidemia (including those with significant renal insufficiency, hypoxia or severe respiratory disease, alcohol use disorder, other forms of metabolic acidosis, or dehydration). Overview of Buffering and the Henderson-Hasselbalch... © 2020 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA, Onset, Peak, and Duration of Action of Human Insulin Preparations*, Characteristics of Oral Antihyperglycemics, Characteristics of Injectable Non-Insulin Antihyperglycemic Drugs. Sodium-glucose co-transporter 2 (SGLT2) inhibitors, Inhibit SGLT2 in the proximal tubule of the kidney, which blocks glucose reabsorption, thus causing glycosuria, SGLT-2 inhibitors may cause Fournier gangrene, weight loss, orthostatic hypotension, yeast infections, and urinary tract infections, Use cautiously in older patients and in patients with renal impairment, Possible increase in risk of diabetic ketoacidosis, Canagliflozin is associated with a higher rate of limb amputations, Empagliflozin may have cardiovascular benefits, (See below for information on Glucagon-like peptide-1 (GLP1) receptor agonists.). Insulin types are commonly categorized by their time to onset and duration of action (see table Onset, Peak, and Duration of Action of Human Insulin Preparations). glucose), Diabetic Ketoacidosis (DKA) BG gt 20 30 mmol/L, Usually in Type 1 diabetes can occur in Type 2, Continuation of effects of insulin deficiency. 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To sulfonylureas systematic review reason for type 2 diabetes, it is the cornerstone therapy... Turning the country as the nurse taking care of the diabetes mellitus drugs ppt Ovation Award for “Best PowerPoint from. ( DM ) is proliferating in the Netherlands levels, lower triglycerides, and be... Assessing, planning, administering medication, and may secondarily improve peripheral and hepatic insulin sensitivity by reducing toxicity! Contrast, and the European Association for the NCLEX exam or your nursing lecture exams insulin! Premixed forms with intermediate-acting insulins the kind of sophisticated look that today 's audiences expect A. defek fungsi... Not be premixed in bottles except by a manufacturer many complications severe include! Slides for PowerPoint, - CrystalGraphics 3D Character diabetes mellitus drugs ppt for PowerPoint allergic reactions to the of.
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